{"id":1951,"date":"2025-07-11T10:32:24","date_gmt":"2025-07-11T02:32:24","guid":{"rendered":"https:\/\/www.vcro.com.tw\/?p=1951"},"modified":"2025-07-11T10:44:46","modified_gmt":"2025-07-11T02:44:46","slug":"new-alzheimers-drug-tml-6-begins-phase-ii-clinical-trials-in-taiwan-and-the-u-s","status":"publish","type":"post","link":"https:\/\/www.vcro.com.tw\/?p=1951","title":{"rendered":"New Alzheimer\u2019s Drug TML-6 Begins Phase II Clinical Trials in Taiwan and the U.S."},"content":{"rendered":"\n<p><strong>Alzheimer\u2019s Health Supplement Proven in Animal Studies to Improve Cognitive Function and Delay Aging<\/strong><\/p>\n\n\n\n<p>In addition to developing the new drug TML-6, <strong>Merry Life Biomedical<\/strong> is also creating preventive and therapeutic health supplements for people at high risk of Alzheimer\u2019s disease. The formulation includes <strong>Theracurmin<\/strong>, a highly bioavailable curcumin imported from Japan, along with <strong>green tea polyphenols<\/strong> known for their anti-aging effects, all optimized through advanced formulation techniques.<\/p>\n\n\n\n<p>Cell and animal studies have confirmed that the supplement offers superior biological activity\u2014<strong>anti-aging, antioxidant, and anti-inflammatory effects<\/strong>\u2014and has <strong>double the absorption rate<\/strong> of Japanese Theracurmin. It has shown effectiveness in <strong>improving cognitive function<\/strong> in Alzheimer\u2019s mouse models and in <strong>reducing amyloid-beta and tau protein accumulation<\/strong> in the brain, thereby helping to delay aging.<\/p>\n\n\n\n<p><strong>Clinical Trials Completed at Three Medical Centers<br>Supplement Shows Potential for Preventing and Improving Alzheimer\u2019s Disease<\/strong><\/p>\n\n\n\n<p>To further validate the supplement\u2019s effects in humans, clinical trials were conducted by <strong>Virginia Contract Research<\/strong> Organization Co., Ltd. (VCRO), a contract research organization (CRO), at three major medical centers in Taiwan. After six months of monitoring, the unblinding of results for 53 participants was completed in <strong>May 2025<\/strong>.<\/p>\n\n\n\n<p>Results showed that participants in the treatment group with higher baseline levels of <strong>blood p-Tau<\/strong> exhibited a <strong>decreasing trend in p-tau217 levels<\/strong>. A <strong>dose-response relationship<\/strong> was also observed, suggesting that the supplement may be effective in both <strong>improving symptoms and preventing the progression<\/strong> of Alzheimer\u2019s disease.<\/p>\n\n\n\n<p><strong>Insights from Alzheimer\u2019s Researcher Professor Gary Small<\/strong><\/p>\n\n\n\n<p>Professor <strong>Gary Small<\/strong>, a renowned brain disease researcher, emphasizes the importance of reducing <strong>inflammatory markers in the brain<\/strong> when managing dementia. He recommends maintaining <strong>good sleep habits<\/strong>, consuming <strong>omega-3 fatty acids<\/strong> from sources like fish and nuts, engaging in <strong>physical activity<\/strong>, staying <strong>socially connected<\/strong>, and <strong>protecting hearing health<\/strong> to reduce oxidative stress and inflammation in the brain.<\/p>\n\n\n\n<p>As someone with personal experience caring for a loved one with dementia, Professor Small also advises families to <strong>educate themselves<\/strong> about the disease\u2019s progression and to <strong>learn appropriate ways to interact with patients<\/strong>. He urges families to seek help from dementia specialists, explore medication options, and focus on <strong>building emotional connections<\/strong> so patients can feel the presence and support of their caregivers. He also encourages joining <strong>support groups<\/strong>, believing that with the right approach, comprehensive care for Alzheimer\u2019s patients is achievable.<\/p>\n\n\n\n<p><strong>For more information, please refer to the source below.<\/strong><br><strong>Source: Medical News Weekly, July 5, 2025 \u2013 Special Report on Dementia<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/www.vcro.com.tw\/wp-content\/uploads\/2025\/07\/alzhemer20250711.png\" alt=\"Alzheimer\" class=\"wp-image-1952\"\/><figcaption class=\"wp-element-caption\">New Alzheimer\u2019s Drug TML-6 Begins Phase II Clinical Trials in Taiwan and the U.S.<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Alzheimer\u2019s Health Supplement Proven in Animal Studies to Improve Cognitive Function and Delay Aging In addition to developing the new drug TML-6, Merry Life Biomedical is also creating preventive and therapeutic health supplements for people at high risk of Alzheimer\u2019s disease. The formulation includes Theracurmin, a highly bioavailable curcumin imported from Japan, along with green [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1952,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[55,56,19,53],"class_list":["post-1951","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-vcro-express","tag-alzheimer","tag-merry-life-biomedical","tag-vcro","tag-virginia-contract-research-organization-co"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>New Alzheimer\u2019s Drug TML-6 Begins Phase II Clinical Trials in Taiwan and the U.S. - VCRO<\/title>\r\n<meta name=\"description\" content=\"New Alzheimer\u2019s Drug TML-6 Begins Phase II Clinical Trials in Taiwan and the U.S. VCRO VCRO express -\" \/>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.vcro.com.tw\/?p=1951\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"New Alzheimer\u2019s Drug TML-6 Begins Phase II Clinical Trials in Taiwan and the U.S. - 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